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Ligand exchange in gold-coated FePt nanoparticles

机译:金涂层Fept纳米粒子中的配体交换

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摘要

In this work we present the magnetic properties of gold coated FePtnanoparticles and the study of stable aqueous dispersions of FePt@Au and FePtsynthesized after ligand exchange with mercaptoundecanoic acid. The particlesize determined from TEM micrographs goes from 4 nm for the uncoatednanoparticles to a maximum of 10 nm for the gold coated ones indicating thatthe thickness of the shell ranges from 1 to 3 nm. The magnetic characterizationconsists in hysteresis cycles at 10 and 300 K. The results show that, at lowfield and room temperature, the magnetic behavior of uncoated and coatednanoparticles are surprisingly quite similar. Since the gold coatednanoparticles keep the magnetic properties of FePt and the presence of goldimproves the functionalization of nanoparticles, the system is suitable forbiological application. Mercaptoundecanoic ligand transfer was used to renderwater stable nanoparticles in a wide pH range. Transmission electron microscopyand dynamic light scattering results show the nanoparticles slightlyagglomerate after ligand exchange. Fourier transform infrared spectroscopyresults suggest that thiol bind to the gold atoms of the surface.
机译:在这项工作中,我们介绍了涂金的FePtnanoparticles的磁性和对与巯基十一烷酸交换配体后合成的FePt @ Au和FePts稳定​​水分散体的研究。由TEM显微照片确定的粒度从未涂覆的纳米颗粒的4 nm到金涂覆的纳米颗粒的最大10 nm,表明壳的厚度为1-3 nm。磁特性包括10 K和300 K的磁滞循环。结果表明,在低场和室温下,未涂覆和涂覆的纳米粒子的磁行为令人惊讶地非常相似。由于镀金的纳米粒子保持FePt的磁性,并且金的存在改善了纳米粒子的功能,因此该系统适用于生物学应用。巯基十一烷配体转移用于使水稳定的纳米粒子在很宽的pH范围内。透射电子显微镜和动态光散射结果表明,配体交换后,纳米颗粒微团聚。傅里叶变换红外光谱结果表明,硫醇与表面的金原子结合。

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